Triclabendazole Side Effects
Medically reviewed by Drugs.com. Last updated on Feb 23, 2024.
Applies to triclabendazole: oral tablet.
Serious side effects of Triclabendazole
Along with its needed effects, triclabendazole may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking triclabendazole:
More common
- Dizziness or lightheadedness
- feeling of constant movement of self or surroundings
- sensation of spinning
Less common
- Back pain
- chest pain, discomfort, or tightness
- cough
- difficulty breathing
- fever
- nausea
- upper right abdominal or stomach pain
- vomiting
- yellow skin or eyes
Other side effects of Triclabendazole
Some side effects of triclabendazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
- Abnormal color of urine
- back pain
- constipation
- difficulty in moving
- itching
- joint pain
- lack or loss of strength
- muscle pain or stiffness
For Healthcare Professionals
Applies to triclabendazole: oral tablet.
Gastrointestinal
Very common (10% or more): Abdominal pain (included upper abdominal pain, abdominal pain; up to 93%), nausea (up to 18%)
Common (1% to 10%): Vomiting, diarrhea
Frequency not reported: Constipation[Ref]
Some side effects associated with this drug treatment in fascioliasis (e.g., abdominal pain) could be secondary to the infection; such effects may be more severe and/or may occur more often in patients with heavy worm burden.[Ref]
Dermatologic
Very common (10% or more): Hyperhidrosis (up to 25%), urticaria (up to 11%)
Common (1% to 10%): Pruritus[Ref]
Metabolic
Very common (10% or more): Decreased appetite (up to 18%)[Ref]
Nervous system
Very common (10% or more): Headache (up to 14%)
Common (1% to 10%): Vertigo[Ref]
Hepatic
Common (1% to 10%): Elevated bilirubin, elevated AST, elevated ALT, jaundice (included jaundice, ocular icterus)
Frequency not reported: Biliary colic, transient increases in liver enzymes, transient increases in total bilirubin
Posttreatment elevations in bilirubin, AST, and ALT were reported in 6.8%, 4.5%, and 3% of patients with normal liver enzyme values at baseline, respectively.
Some side effects associated with this drug treatment in fascioliasis (e.g., biliary colic, jaundice) could be secondary to the infection; such effects may be more severe and/or may occur more often in patients with heavy worm burden.
Respiratory
Common (1% to 10%): Dyspnea, cough[Ref]
Other
Common (1% to 10%): Elevated alkaline phosphatase, asthenia, chest pain, pyrexia, chest discomfort
Postmarketing reports: Drug resistance[Ref]
Posttreatment elevations in alkaline phosphatase were reported in 4.2% of patients with normal liver enzyme values at baseline.
Resistance to this drug has been reported outside the US.[Ref]
Musculoskeletal
Common (1% to 10%): Musculoskeletal chest pain
Frequency not reported: Arthralgia, back pain, spinal pain[Ref]
Genitourinary
Frequency not reported: Chromaturia[Ref]
More about triclabendazole
- Check interactions
- Compare alternatives
- Reviews (1)
- Dosage information
- During pregnancy
- Drug class: anthelmintics
- Breastfeeding
Patient resources
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References
1. Product Information. Egaten (triclabendazole). Novartis Pharmaceuticals. 2019.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.