Tofersen Side Effects
Medically reviewed by Drugs.com. Last updated on Aug 17, 2023.
Applies to tofersen: intrathecal solution.
Serious side effects of Tofersen
Along with its needed effects, tofersen may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking tofersen:
More common
- Arm, leg, or back pain
- difficulty in moving
- joint pain or swelling
- muscle aches, cramps, pains, or stiffness
- nerve pain
- unusual tiredness or weakness
Less common
- Back numbness, tingling, or weakness
- blurred vision
- change in ability to see colors, especially blue or yellow
- confusion
- fever
- headache
- severe nausea or vomiting
- stiff neck
For Healthcare Professionals
Applies to tofersen: intrathecal solution.
General
The most common adverse reactions occurring in 10% of patients or greater included pain, fatigue, arthralgia, increased cerebrospinal fluid white blood cells, and myalgia.[Ref]
Immunologic
Very common (10% or more): Anti-drug antibodies (58.4%)[Ref]
Musculoskeletal
Very common (10% or more): Arthralgia (14%), myalgia (14%), musculoskeletal stiffness (6%)[Ref]
Nervous system
Very common (10% or more): Cerebrospinal fluid white blood cells increased or pleocytosis (14%)
Common (1% to 10%): Cerebrospinal fluid proteins increased (8%), neuralgia (6%), myelitis and radiculitis (4%), elevated intracranial pressure and/or papilledema (2.7%), aseptic meningitis (1.4%)[Ref]
Other
Very common (10% or more): Pain including extremity and back pain (42%), fatigue (17%)
Frequency not reported: Pyrexia[Ref]
More about tofersen
- Compare alternatives
- Dosage information
- During pregnancy
- Drug class: miscellaneous central nervous system agents
- Breastfeeding
- En español
Patient resources
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Related treatment guides
References
1. Product Information. Qalsody (tofersen). Biogen Idec Inc. 2023;1.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.