Leniolisib Side Effects

Medically reviewed by Drugs.com. Last updated on Apr 23, 2023.

Applies to leniolisib: oral tablet.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• liver problems--loss of appetite, nausea, vomiting, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

• headache;

• dry or thickened skin, itching, rash; or

• cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to leniolisib: oral tablet.

General

The most common side effects in greater than 10% of patients were headache, sinusitis, and atopic dermatitis.^[Ref]

Cardiovascular

Very common (10% or more): Tachycardia/sinus tachycardia (10%)^[Ref]

Dermatologic

Very common (10% or more): Atopic dermatitis/eczema (14%), alopecia (10%)^[Ref]

Gastrointestinal

Very common (10% or more): Diarrhea (10%)^[Ref]

Musculoskeletal

Very common (10% or more): Back pain (10%), neck pain (10%)^[Ref]

Nervous system

Very common (10% or more): Headache (24%)^[Ref]

Other

Very common (10% or more): Sinusitis (19%), fatigue (10%), pyrexia (10%), decreased absolute neutrophil count (33%)^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer