Apadamtase alfa, recombinant Side Effects

Medically reviewed by Drugs.com. Last updated on Feb 15, 2024.

Applies to apadamtase alfa, recombinant: intravenous powder for solution.

Serious side effects

Along with its needed effects, apadamtase alfa, recombinant may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking apadamtase alfa, recombinant:

More common

• Body aches or pain
• chills
• cough
• ear congestion
• fever
• headache, severe and throbbing
• loss of voice
• sneezing
• sore throat
• stuffy or runny nose
• trouble breathing
• unusual tiredness or weakness

Incidence not known

• Blurred vision
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• chest tightness
• confusion
• difficulty swallowing
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fast, pounding, or irregular heartbeat or pulse
• hives, itching, skin rash
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• nausea
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• restlessness
• unusual drowsiness, dullness, or feeling of sluggishness
• vomiting

Other side effects

Some side effects of apadamtase alfa, recombinant may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Diarrhea
• stomach pain

For Healthcare Professionals

Applies to apadamtase alfa, recombinant: intravenous kit.

General

The most common adverse reactions reported in 5% or more patients were headache, diarrhea, migraine, abdominal pain, nausea, upper respiratory tract infection, dizziness, and vomiting.^[Ref]

Gastrointestinal

Very common (10% or more): Diarrhea (16.7%), abdominal pain (12.5%), nausea (12.5%), vomiting (10.4%)^[Ref]

Respiratory

Very common (10% or more): Upper respiratory tract infection (12.5%)^[Ref]

Nervous system

Very common (10% or more): Headache (31.3%), migraine (14.6%), dizziness (10.4%)^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer