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Anacaulase topical Side Effects

Medically reviewed by Drugs.com. Last updated on Jun 27, 2023.

Applies to anacaulase topical: topical application gel/jelly.

Serious side effects of Anacaulase topical

Along with its needed effects, anacaulase topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking anacaulase topical:

More common

Less common

Incidence not known

Other side effects of Anacaulase topical

Some side effects of anacaulase topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to anacaulase topical: topical gel.

Cardiovascular

Common (1% to 10%): Tachycardia[Ref]

Dermatologic

Very common (10% or more): Pruritus (15%)

Common (1% to 10%): Decubitus ulcer, rash, scar[Ref]

Gastrointestinal

Common (1% to 10%): Vomiting[Ref]

General

The most common adverse reactions with a frequency of greater than 10% were pruritus and pyrexia.

Genitourinary

Common (1% to 10%): Urinary tract infection[Ref]

Hematologic

Common (1% to 10%): Anemia, hypotension, leukocytosis, subcutaneous hematoma[Ref]

Hepatic

Common (1% to 10%): Abnormal hepatic function[Ref]

Hypersensitivity

Common (1% to 10%): Drug hypersensitivity

Postmarketing reports: Hypersensitivity (including anaphylaxis and urticaria)[Ref]

Local

Common (1% to 10%): Wound complication[Ref]

Wound complication includes skin graft failure, graft loss, graft complication, and wound decomposition.[Ref]

Nervous system

Very common (10% or more): Pyrexia (12%)

Common (1% to 10%): Insomnia[Ref]

Other

Common (1% to 10%): Bacteremia, infection, sepsis[Ref]

References

1. Product Information. Nexobrid (anacaulase topical). Vericel Corporation. 2022.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.