Allogeneic processed thymus tissue Side Effects
Applies to allogeneic processed thymus tissue: intramuscular implant.
Cardiovascular
Very common (10% or more): Hypertension (19%)[Ref]
Dermatologic
Very common (10% or more): Rash (15%)
Frequency not reported: Granuloma skin, urticaria[Ref]
Rash includes rash, granuloma skin, rash popular, urticaria.[Ref]
Gastrointestinal
Diarrhea includes diarrhea and hemorrhagic diarrhea.[Ref]
Common (1% to 10%): Diarrhea[Ref]
General
The most common adverse reactions reported were hypertension, cytokine release syndrome, rash, hypomagnesemia, renal impairment/failure, thrombocytopenia, and graft versus host disease.[Ref]
Hematologic
Very common (10% or more): Thrombocytopenia (12%)
Common (1% to 10%): Hemolytic anemia, neutropenia[Ref]
-Thrombocytopenia includes thrombocytopenia and immune thrombocytopenic purpura.
-Hemolytic anemia includes autoimmune hemolytic anemia, Coombs-positive hemolytic anemia, hemolysis, hemolytic anemia.[Ref]
Immunologic
Very common (10% or more): Cytokine release syndrome (18%), graft versus host disease (10%)[Ref]
Graft versus host disease (GVHD) includes GVHD, GVHD-gut, GVHD-skin, omenn syndrome.[Ref]
Metabolic
Very common (10% or more): Hypomagnesemia (16%)
Common (1% to 10%): Acidosis[Ref]
Acidosis includes acidosis and blood bicarbonate decreased.[Ref]
Nervous system
Common (1% to 10%): Seizure[Ref]
Seizures include infantile spasms, seizures, and febrile convulsion.[Ref]
Other
Common (1% to 10%): Pyrexia[Ref]
Renal
Very common (10% or more): Renal impairment/failure (12%)
Common (1% to 10%): Proteinuria
Frequency not reported: Acute kidney injury, blood creatinine increased, renal tubular acidosis[Ref]
Respiratory
Common (1% to 10%): Respiratory distress[Ref]
Respiratory distress includes respiratory distress, hypoxia, respiratory failure.[Ref]
More about allogeneic processed thymus tissue
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- During pregnancy
- Drug class: other immunostimulants
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References
1. Product Information. Rethymic (allogeneic processed thymus tissue). Enzyvant Therapeutics Inc. 2021;1.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
