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Acetaminophen / caffeine / chlorpheniramine / hydrocodone / phenylephrine Side Effects

Applies to acetaminophen/caffeine/chlorpheniramine/hydrocodone/phenylephrine: oral tablet.

Cardiovascular

Cardiovascular side effects have included hypertension, postural hypotension, tachycardia, and palpitations.[Ref]

Genitourinary

Genitourinary side effects have included ureteral spasm, spasm of vesicle sphincters, and urinary retention.[Ref]

Nervous system

Nervous system side effects have included sedation, drowsiness, mental clouding, lethargy, and impairment of mental and physical performance.[Ref]

Psychiatric

Psychiatric side effects have included anxiety, fear, dysphoria, psychic dependence, and mood changes.[Ref]

Ocular

Ocular side effects have included blurred vision.[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting.[Ref]

Respiratory

Respiratory side effects have included dose-related respiratory depression.[Ref]

More about acetaminophen / caffeine / chlorpheniramine / hydrocodone / phenylephrine

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References

1. Product Information. Hycomine Compound (APAP/caffeine/CPM/hydrocodone/PE). Endo Laboratories LLC. 2022.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.