5-HTP Side Effects

Generic name: 5-hydroxytryptophan

Note: This document contains side effect information about 5-hydroxytryptophan. Some dosage forms listed on this page may not apply to the brand name 5-HTP.

Applies to 5-hydroxytryptophan: oral capsule, oral tablet, oral tablet disintegrating, oral tablet extended release.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Stop using 5-hydroxytryptophan (the active ingredient contained in 5-HTP) and call your healthcare provider at once if you have:

• slow heart rate, feeling like you might pass out;

• skin rash, bruising; or

• racing thoughts, increased energy, decreased need for sleep, risk-taking behavior, being agitated or talkative.

Common side effects may include:

• drowsiness, sleep problems (insomnia);

• headache, dizziness, weakness;

• altered sense of taste, appetite or weight change;

• muscle problems;

• severe vomiting, stomach pain, heartburn;

• diarrhea, constipation; or

• sexual problems.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer