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Does Gemtesa (vibegron) cause weight gain?

Medically reviewed by Carmen Pope, BPharm. Last updated on April 24, 2024.

Official answer

by Drugs.com

Weight gain is not listed as a side effect of Gemtesa (vibegron) in the product information and there does not seem to be any anecdotal reports of weight gain from blog sites or Gemtesa reviews. Gemtesa does not cause weight gain.

It is possible that beta-3 agonists, such as Gemtesa, could promote weight loss. A small study that investigated mirabegron, another beta-3 agonists used for OAB, found that it also activated beta-3 receptors located in brown fat (adipose) tissue which boosted the participants' ability to burn energy, increasing the number of calories they burned. But this was a preliminary study and larger trials are needed.

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