Skip to main content

Cyramza FDA Approval History

Last updated by Judith Stewart, BPharm on Jan 27, 2021.

FDA Approved: Yes (First approved April 21, 2014)
Brand name: Cyramza
Generic name: ramucirumab
Dosage form: Injection
Company: Eli Lilly and Company
Treatment for: Gastric Cancer, Non Small Cell Lung Cancer, Colorectal Cancer, Hepatocellular Carcinoma

Cyramza (ramucirumab) is a human vascular endothelial growth factor receptor 2 (VEGFR2) antagonist indicated:

Development timeline for Cyramza

DateArticle
Oct  9, 2023First Patient Dosed in the Phase 3 Clinical Study of Efdamrofusp Alfa For the Treatment of Neovascular Age-related Macular Degeneration
May 29, 2020Approval Lilly's Cyramza (ramucirumab) Receives FDA Approval as First-Line Treatment for Metastatic EGFR-Mutated Non-Small Cell Lung Cancer
May 13, 2019Approval Lilly's Cyramza (ramucirumab) Becomes First FDA-Approved Biomarker-Driven Therapy in Patients with Hepatocellular Carcinoma
Apr 24, 2015Approval FDA Approves Cyramza (Ramucirumab) for Use with FOLFIRI in Second-Line Treatment of Metastatic Colorectal Cancer
Dec 12, 2014Approval FDA Expands Approved use of Cyramza to Treat Aggressive Non-Small Cell Lung Cancer
Nov  5, 2014Approval FDA Approves Cyramza (ramucirumab) in Combination with Paclitaxel for Advanced Gastric Cancer after Prior Chemotherapy
Apr 21, 2014Approval FDA Approves Cyramza for Stomach Cancer

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.