ActoPlus Met XR Interactions
There are 445 drugs known to interact with ActoPlus Met XR (metformin/pioglitazone), along with 14 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 31 are major, 401 are moderate, and 13 are minor.
- View all 445 medications that may interact with ActoPlus Met XR
- View ActoPlus Met XR alcohol/food interactions (4)
- View ActoPlus Met XR disease interactions (14)
Most frequently checked interactions
View interaction reports for ActoPlus Met XR (metformin / pioglitazone) and the medicines listed below.
- Abilify (aripiprazole)
- Actos (pioglitazone)
- Adalat CC (nifedipine)
- Aspir 81 (aspirin)
- aspirin
- Aspirin Low Strength (aspirin)
- atorvastatin
- BuSpar (buspirone)
- Cialis (tadalafil)
- Clarinex (desloratadine)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Effexor (venlafaxine)
- Exforge (amlodipine / valsartan)
- ferrous sulfate
- Flomax (tamsulosin)
- glimepiride
- Glucovance (glyburide / metformin)
- glyburide
- hydrochlorothiazide
- Januvia (sitagliptin)
- Jardiance (empagliflozin)
- Keppra (levetiracetam)
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Levemir (insulin detemir)
- Lexapro (escitalopram)
- pravastatin
- Victoza (liraglutide)
- Vitamin D3 (cholecalciferol)
ActoPlus Met XR alcohol/food interactions
There are 4 alcohol/food interactions with ActoPlus Met XR (metformin / pioglitazone).
ActoPlus Met XR disease interactions
There are 14 disease interactions with ActoPlus Met XR (metformin / pioglitazone) which include:
- lactic acidosis
- liver disease
- renal dysfunction
- CHF
- type I diabetes
- hypoglycemia
- B12 deficiency
- bladder cancer
- edema
- liver disease
- macular edema
- premenopausal anovulation
- weight gain
- anemia
Report options
More about ActoPlus Met XR (metformin / pioglitazone)
- ActoPlus Met XR consumer information
- Compare alternatives
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: antidiabetic combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
