Promethazine with Dextromethorphan Interactions
There are 725 drugs known to interact with Promethazine with Dextromethorphan (dextromethorphan / promethazine), along with 18 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 158 are major, 553 are moderate, and 14 are minor.
- View all 725 medications that may interact with Promethazine with Dextromethorphan
- View Promethazine with Dextromethorphan alcohol/food interactions (1)
- View Promethazine with Dextromethorphan disease interactions (18)
Most frequently checked interactions
View interaction reports for Promethazine with Dextromethorphan (dextromethorphan / promethazine) and the medicines listed below.
- acetaminophen
- acetaminophen / oxycodone
- albuterol
- Aleve (naproxen)
- amlodipine
- amoxicillin
- atorvastatin
- azelastine nasal
- benzonatate
- cephalexin
- famotidine
- Flexeril (cyclobenzaprine)
- fluconazole
- folic acid
- gabapentin
- hydroxyzine
- ibuprofen
- levothyroxine
- lisinopril
- loratadine
- lorazepam
- methocarbamol
- Metoprolol Succinate ER (metoprolol)
- montelukast
- naproxen
- omeprazole
- prednisone
- tramadol
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Promethazine with Dextromethorphan alcohol/food interactions
There is 1 alcohol/food interaction with Promethazine with Dextromethorphan (dextromethorphan / promethazine).
Promethazine with Dextromethorphan disease interactions
There are 18 disease interactions with Promethazine with Dextromethorphan (dextromethorphan / promethazine) which include:
- acute alcohol intoxication
- cardiovascular disease
- CNS depression
- head injury
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- dystonic reactions
- hematologic toxicity
- liver disease
- NMS
- parkinsonism
- renal dysfunction
- seizure disorders
- tardive dyskinesia
- antidopaminergic effects 2
More about Promethazine with Dextromethorphan (dextromethorphan / promethazine)
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.