Periostat Dosage

THE DOSAGE OF PERIOSTAT DIFFERS FROM THAT OF DOXYCYCLINE USED TO TREAT INFECTIONS. EXCEEDING THE RECOMMENDED DOSAGE MAY RESULT IN AN INCREASED INCIDENCE OF SIDE EFFECTS INCLUDING THE DEVELOPMENT OF RESISTANT MICROORGANISMS.

PERIOSTAT 20 mg twice daily as an adjunct following scaling and root planing may be administered for up to 9 months. PERIOSTAT should be taken twice daily at 12 hour intervals, usually in the morning and evening. It is recommended that if PERIOSTAT is taken close to meal times, allow at least one hour prior to or two hours after meals. Safety beyond 12 months and efficacy beyond 9 months have not been established.

Administration of adequate amounts of fluid along with the tablets is recommended to wash down the drug and reduce the risk of esophageal irritation and ulceration. (See ADVERSE REACTIONS section).