Anjeso Dosage

Use for the shortest duration consistent with individual patient treatment goals [see Warnings and Precautions (5)].

For intravenous administration only.

The recommended dose of ANJESO is 30 mg once daily, administered by intravenous bolus injection over 15 seconds.

When initiating ANJESO, monitor patient analgesic response. Because the median time to meaningful pain relief was 2 and 3 hours after ANJESO administration in two clinical studies, a non-NSAID analgesic with a rapid onset of effect may be needed, for example, upon anesthetic emergence or resolution of local or regional anesthetic blocks [see Clinical Studies (14)].

Some patients may not experience adequate analgesia for the entire 24-hour dosing interval and may require administration of a short-acting, non-NSAID, immediate-release analgesic [see Clinical Studies (14)].

To reduce the risk of renal toxicity, patients must be well hydrated prior to administration of ANJESO.

Visually inspect parenteral drug products for particulate matter and discoloration prior to administration. Should the contents appear discolored or contain particulate matter, discard the vial [see Dosage Forms and Strengths (3)]. The vial contains overfill to allow for withdrawal of 1 mL of the drug product. The overfill is to provide assurance that 1 mL can be withdrawn from the vial to deliver 30 mg of meloxicam. Discard any unused portion from the single-dose vial [see Dosage Forms and Strengths (3)].