Seroquel XR Alternatives Compared
Seroquel XR | Trintellix | Wellbutrin XL |
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Seroquel XR (quetiapine) | Trintellix (vortioxetine) | Wellbutrin XL (bupropion) |
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Prescription only
Prescribed for Bipolar Disorder, Schizoaffective Disorder, Depression, Schizophrenia, Major Depressive Disorder. Seroquel XR may also be used for purposes not listed in this medication guide. |
Prescription only
Trintellix may be used to treat depression in adults. It is different from other antidepressants currently on the market because it directly affects serotonin receptors as well as inhibits serotonin... View more |
Prescription only
Prescribed for Major Depressive Disorder, Depression, Seasonal Affective Disorder. Wellbutrin XL may also be used for purposes not listed in this medication guide. |
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More about Seroquel XR (quetiapine) | More about Trintellix (vortioxetine) | More about Wellbutrin XL (bupropion) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Seroquel XR has an average rating of 7.1 out of 10 from a total of 226 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 19% reported a negative effect. |
Trintellix has an average rating of 6.0 out of 10 from a total of 1101 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 33% reported a negative effect. |
Wellbutrin XL has an average rating of 7.5 out of 10 from a total of 482 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 15% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Seroquel XR side effects in more detail. |
See also: Trintellix side effects in more detail. |
See also: Wellbutrin XL side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Seroquel XR prices |
View all Trintellix prices |
View all Wellbutrin XL prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Other quetiapine brands include: Seroquel |
N/A |
Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
6 hours |
66 hours |
30 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 708 drugs are known to interact with Seroquel XR:
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A total of 347 drugs are known to interact with Trintellix:
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A total of 497 drugs are known to interact with Wellbutrin XL:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
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First Approval Date | ||||||||||||||||||||||||||
May 17, 2007 |
September 30, 2013 |
August 28, 2003 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.