Tumor Lysis Syndrome
Medically reviewed by Drugs.com. Last updated on May 6, 2024.
Tumor lysis syndrome (TLS) is a condition that happens when cancer cells die quickly. Dying cells release large amounts of potassium, phosphate, and uric acid into the blood. This can cause heart or kidney problems and lead to kidney failure. TLS can become life-threatening if is not managed or treated. It most commonly happens after chemotherapy or radiation treatment, but may also occur after other forms of cancer treatment.
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Medicines:
- Uric acid medicine decreases uric acid levels in your blood.
- Loop diuretics are given after IV fluids to help you urinate more.
Monitoring:
- Daily intake and output helps healthcare providers keep track of how much you drink and urinate. Ask healthcare providers if they need to measure or collect your urine.
- You will be weighed once a day to check if you are retaining or losing too much fluid. Young children will have their weight measured twice daily.
- Telemetry is continuous monitoring of your heart rhythm. Sticky pads placed on your skin connect to an EKG machine that records your heart rhythm.
Tests:
Blood tests are done to check potassium, calcium, phosphate, and uric acid levels. They also help healthcare providers monitor your kidney function.
Treatment:
- IV fluids help you stay hydrated and urinate more.
- Dialysis may be needed to decrease potassium levels in your blood. It also helps protect your heart and kidneys.
RISKS:
TLS increases your risk for an irregular heart rate or seizures. It also increases your risk for kidney problems that may lead to kidney failure. TLS and these conditions may become life-threatening.
CARE AGREEMENT:
You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment.© Copyright Merative 2024 Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
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