Enterisol Ileitis (Canada)

Company: Boehringer

Lawsonia Intracellularis Vaccine

Avirulent Live Culture

For use in swine only

Enterisol Ileitis Indications

Recommended for the vaccination of healthy, susceptible swine 3 weeks of age or older as an aid in the prevention and control of porcine proliferative enteropathy (Ileitis) caused by Lawsonia intracellularis. In clinical studies, this vaccine significantly prevented gross and microscopic intestinal lesions of Ileitis and significantly prevented colonization of virulent L. intracellularis after challenge.

Directions

Rehydrate the vaccine by adding the full contents of the accompanying sterile water diluent to the vaccine vial. Shake well and use immediately.

Vaccination By Oral Drenching

Administer a single dose orally. The dose volume is as follows:

- 50 dose/100 mL presentation: one 2 mL dose per pig.

- 100 dose/100 mL presentation: one 1 mL dose per pig.

Vaccination Via The Drinking Water

Conventional Water Directions (Open Trough or Barrel Type [Tank] System)

1. Do not reconstitute the vaccine until ready to vaccinate.

2. Remove all medications, sanitizers, and disinfectants from drinking water a minimum of 72 hours (3 days) prior to and following vaccination.

3. Flush watering system with nonchlorinated/nontreated clean water to eliminate any antibacterial agents.

4. Reconstitute vaccine according to directions.

5. Add number of doses of vaccine equal to or more than the number of pigs to vaccinate, to the appropriate amount of clean, nontreated drinking water (see table).

6. Final solution containing vaccine should be consumed within 4 hours after reconstitution of the vaccine.

Directions For Automatic Watering Systems Equipped With Proportioner

Several types of medicators/proportioners are commercially available.

1. Do not reconstitute the vaccine until ready to vaccinate.

2. Remove all medications, sanitizers, and disinfectants from drinking water a minimum of 72 hours (3 days) prior to and following vaccination.

3. Provide sufficient watering space so that all pigs can drink within a 4-hour time frame.

4. Flush watering system with nontreated clean water to eliminate any antibacterial agents.

5. Set proportioner to deliver 30 mL (1 oz) of vaccine solution per 3.8 litres (1 US gallon) of water.

6. See Table to determine how many ounces of stock solution to prepare for pounds of pig to vaccinate.

7. Prepare vaccine concentrate as follows:

a. Reconstitute vaccine according to directions.

b. Add appropriate amount of clean, nontreated water to the container used for the stock solution.

c. Add number of doses to the stock solution container equal to or more than the number of pigs to vaccinate.

d. Mix thoroughly.

8. Insert proportioner hose into vaccine concentrate and start water flow. Continue until all concentrate has been consumed before changing water supply to direct flow. Do not medicate or use disinfectants for at least 3 days following vaccination.

¹ Based on 0.64 L (0.17 gal) consumed per 45.4 kg (100 lbs) body weight in 4-hour period.

² Values for pigs 18 kg (40 lbs) or bigger.

Enterisol Ileitis Caution

The actual amount of water consumed may vary considerably depending on several factors, including environmental temperature. It is recommended to pre-measure the actual stock solution volume requirements the day prior to vaccination, during the planned vaccination time period. This should be done to accurately estimate the stock solution volume needed in order to ensure that the vaccine is consumed within the 4-hour recommended time frame.

Incompatibility

All materials used in administration of this vaccine must be free of antibiotic and disinfectant residue to prevent vaccine inactivation and reduced product efficacy.

Precautions

Store at 2-7°C. Do not freeze. After reconstitution, shake well and use entire contents immediately. Do not vaccinate within 21 days before slaughter. Burn container and all unused contents. Do not use in pregnant swine or breeding boars. Do not use concurrently with antibiotics. All materials used in administering this vaccine must be free of antimicrobial or disinfectant residue to prevent inactivation and reduced product efficacy. Anaphylactic reactions may occur. Antidote: Epinephrine.

Manufactured by: Boehringer Ingelheim Vetmedica, Inc., St. Joseph, Missouri 64506 U.S.A.

U.S. Veterinary License No. 124

Manufactured for: Boehringer Ingelheim (Canada) Ltd., Burlington, Ontario L7L 5H4

30412-01

Presentation: 50 doses and 100 doses.

CPN: 12300561