Taltz Side Effects
Generic name: ixekizumab
Note: This document contains side effect information about ixekizumab. Some dosage forms listed on this page may not apply to the brand name Taltz.
Applies to ixekizumab: subcutaneous solution.
Serious side effects of Taltz
Along with its needed effects, ixekizumab (the active ingredient contained in Taltz) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking ixekizumab:
More common
- Body aches or pain
- burning, dry, or itching eyes
- chills
- cough
- difficulty with breathing
- discharge or excessive tearing
- ear congestion
- fever
- headache
- hoarseness
- itching in the genital or other skin areas
- loss of voice
- lower back or side pain
- painful or difficult urination
- redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
- runny or stuffy nose
- scaling of the skin
- sneezing
- sore mouth or tongue
- sore throat
- unusual tiredness or weakness
- white patches in the mouth or on the tongue
Less common
- Chest tightness
- diarrhea
- difficulty swallowing
- dizziness
- fast heartbeat
- general feeling of discomfort or illness
- hives, itching, skin rash
- joint pain
- loss of appetite
- muscle aches and pains
- nausea
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- shivering
- sweating
- trouble sleeping
- vomiting
Rare
- Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- rectal bleeding
- redness of the skin
- severe diarrhea
- severe stomach pain
Other side effects of Taltz
Some side effects of ixekizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
For Healthcare Professionals
Applies to ixekizumab: subcutaneous solution.
General
Most commonly reported adverse reactions with a frequency of 1% or greater were injection site reactions, upper respiratory tract infections, nausea, and tinea infections.
Cardiovascular
Common (1% to 10%): Hypertension
Dermatologic
Common (1% to 10%): Urticaria, herpes simplex (mucocutaneous)
Uncommon (0.1% to 1%): Angioedema, cellulitis, rash, eczema, pruritus, alopecia[Ref]
Gastrointestinal
Common (1% to 10%): Nausea, diarrhea, oral herpes, pharyngitis, oropharyngeal pain
Uncommon (0.1% to 1%): Oral candidiasis, inflammatory bowel disease, abdominal pain
Rare (0.01% to 0.1%): Oesophageal candidiasis
Frequency not reported: Crohn's disease, ulcerative colitis, gastroenteritis[Ref]
Genitourinary
Common (1% to 10%): Vulvovaginal candidiasis, menstrual disorder, irregular menstruation, uterine dilation, curettage
Uncommon (0.1% to 1%): Ovarian cyst
Frequency not reported: Bacterial vaginosis, bartholinitis
Hematologic
Very common (10% or more): Neutropenia (Up to 11%)
Common (1% to 10%): Thrombocytopenia, anemia[Ref]
Hypersensitivity
Frequency not reported: Serious hypersensitivity reactions (e.g., anaphylaxis, angioedema, urticaria)[Ref]
Immunologic
Very common (10% or more): Infections ( Up to 27%), immunogenicity (Up to 22%)
Common (1% to 10%): Tinea infections, influenza
Uncommon (0.1% to 1%): Serious infections[Ref]
Local
Very common (10% or more): Injection site reactions (Up to 17%)
Frequency not reported: Erythema, pain
Postmarketing reports: Esophageal candidiasis[Ref]
Musculoskeletal
Common (1% to 10%): Arthralgia, back pain, myalgia
Uncommon (0.1% to 1%): Musculoskeletal pain, neck pain, non-cardiac chest pain
Nervous system
Uncommon (0.1% to 1%): Headache, dizziness
Ocular
Common (1% to 10%): Conjunctivitis
Uncommon (0.1% to 1%): Iridocyclitis, eye pain[Ref]
Other
Common (1% to 10%): Anti-drug antibodies development
Uncommon (0.1% to 1%): Fatigue, pyrexia
Psychiatric
Common (1% to 10%): Depression
Respiratory
Very common (10% or more): Upper respiratory tract infections (including nasopharyngitis and rhinovirus infection) (Up to 16%)
Uncommon (0.1% to 1%): Rhinitis, bronchitis, sinusitis[Ref]
Metabolic
Uncommon (0.1% to 1%): Increased blood creatine phosphokinase, increased aspartate aminotransferase
Renal
Common (1% to 10%): Dysuria
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More about Taltz (ixekizumab)
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- Reviews (207)
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- Dosage information
- Patient tips
- During pregnancy
- FDA approval history
- Drug class: interleukin inhibitors
- Breastfeeding
Patient resources
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Related treatment guides
References
1. Cerner Multum, Inc. UK Summary of Product Characteristics.
2. Cerner Multum, Inc. Australian Product Information.
3. Product Information. Taltz Autoinjector (ixekizumab). Eli Lilly and Company. 2016.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
