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Brivaracetam Dosage

Medically reviewed by Drugs.com. Last updated on May 15, 2024.

Applies to the following strengths: 10 mg; 25 mg; 50 mg; 75 mg; 100 mg; 10 mg/mL

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Epilepsy

Initial dose: 50 mg orally 2 times a day

Maintenance dose: 25 mg to 100 mg orally twice a day based on clinical response and tolerability
Maximum dose: 200 mg/day

IV Administration:

Comments:

Use: For the treatment of partial-onset seizures

Usual Pediatric Dose for Epilepsy

1 month to 16 years:


16 years of age and older:
Initial dose: 50 mg orally 2 times a day
Maintenance dose: 25 mg to 100 mg orally twice a day

IV Administration: May be used in patients 16 years or older when oral administration is temporarily not feasible

Comments:

Use: For the treatment of partial-onset seizures in patients 1 month or older

Renal Dose Adjustments

Mild, moderate, or severe renal dysfunction: No adjustment recommended
ESRD undergoing dialysis: Not recommended

Liver Dose Adjustments

Adults and Pediatric Patients: Weight: 50 kg or greater:


Pediatric Patients: Weight: 20 kg to less than 50 kg:

Pediatric Patients: Weight: 11 kg to less than 20 kg:

Pediatric Patients: Weight: Less than 11 kg:

Dose Adjustments

Elderly: Dose selection should be judicious, generally starting at the low end of dosing range

Concomitant Administration with Rifampin:


Discontinuation:

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 1 month.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule V

Dialysis

Not recommended

Other Comments

Administration Advice:
Oral Tablets and Oral Solution:


IV Administration:

Storage Requirements:

IV Preparation Techniques:

General:

Monitor:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.